Thiocolchicoside Capsule

Thiocolchicoside Capsule
Thiocolchicoside Capsule
Price And Quantity
  • Box/Boxes
  • 300
  • Box/Boxes
  • 76 INR
    Product Specifications
    • General Medicines
    • Capsules
    • Adults
    • Cool and Dry Place
      Product Description
      Thiocolchicoside, is a synthetic sulphur derivative of colchicoside, a naturally occurring glucosidecontained in theColchicum autumnale plant Thiocolchicoside has a selective affinity for g-amino-butyric acid (GABA) receptors and actson themuscular contracture by activating the GABA-nergicinhibitory pathways thereby acting as a potent mus-clerelaxant Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. Itacts as a competitive GABAA receptor antagonist and also inhibits glycine receptors with similar potency and nicotinicacetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizureproneindividuals. Mode of action includes modulation of chemokine and prostanoid production and inhibition ofneutrophil and endothelial cell adhesion molecules by which it interferes with the initiation and amplification of the jointinflammation.

      Backache, Neuralgia, Pain, Parkinsonism, Sciatic pain.

      Thiocolchicoside is contraindicated in conditions like Flaccid paralysis, Muscular hypotonia.

      Thiocolchicoside is a muscle relaxant which has been claimed to possess GABA-mimetic and glycinergic actions.

      Potent competitive antagonist of GABA function.
      A muscle relaxant and displays anti-inflammatory and analgesic propertiesFollowing oral administration, thiocolchicoside is well absorbed from the gastrointestinal tract.
      It shows its effect in 1-2 hours after oral administration and peak plazma level is achieved in about 0.7 hoursElimination half-life is about 2.5-5 hours. Its effect is continued for 24 hours.

      Adverse Effects:
      Most of adverse reactions observed in clinical trials were of a mild and transient nature. The most commonly seen adverse reactions in clinical trials of the tablet formulation were gastrointestinal and also adverse reaction have been reported for cephalosporin sensitive person and also in some cases somnolence, nasopharyngitis, fatigue, dry mouth and pharyngitis, and most were mild to moderate in intensity.

      Side Effects:
      The symptomatic adverse reactions produced by Thiocolchicoside are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea.

      Storage :
      Store in a cool dry place. Protect from light.
      Trade Information
      • Cash in Advance (CID), Cash Advance (CA)
      • 300 Per Month
      • 1 Months
      • Yes
      • Sample costs shipping and taxes has to be paid by the buyer
      • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
      • All India
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